The Klenke Bowl is held yearly in loving memory of Kraig Klenke MPS and ML disorders affect major organs including the respiratory system, heart, bones and even the nervous system. MPS and ML primarily affect children; it is caused by the body's inability to produce certain enzymes. At the present time, there is no cure. The National MPS Society is a non-profit organization dedicated to those individuals and their families affected with MPS and related disorders.